Does cervical disc arthroplasty have lower incidence of dysphagia than anterior cervical discectomy and fusion? A meta-analysis

Clin Neurol Neurosurg. 2016 Jul:146:45-51. doi: 10.1016/j.clineuro.2016.04.002. Epub 2016 Apr 4.

Abstract

Objective: Dysphagia is a common occurrence after anterior cervical spine surgery. The aim of this meta-analysis was to evaluate the incidence of dysphagia after ervical disc arthroplasty (CDA) compared with anterior cervical discectomy and fusion (ACDF).

Material and methods: The electronic databases, including PubMed, EMBASE and Cochrane Central Register of Controlled Trials, were searched to identify the randomized controlled trials comparing CDA with ACDF. Studies were included only if the incidence of postoperative dysphagia was investigated. Study selection, "risk of bias" assessment, and data extraction were independently performed by two investigators. Data analyses were conducted with RevMan 5.3 software.

Results: Ten studies involving 2711 patients (CDA group, n=1512; ACDF group, n=1199) were identified. All studies were determined to have a low risk of bias. Pooling analysis of these studies showed that the incidence of dysphagia was 9.46% (143/1512) after CDA versus 12.09% (145/1199) after ACDF. Meta-analysis showed the statistical difference between two groups with regards to the incidence of dysphagia (risk ratio 0.76; 95% confidence interval [0.61, 0.94]; P=0.01).

Conclusion: This meta-analysis indicates that patients have a significantly lower incidence of dysphagia after CDA than after ACDF. Additional studies are needed.

Keywords: Anterior cervical discectomy and fusion; Cervical disc arthroplasty; Dysphagia; Incidence; Meta-analysis; Randomized controlled trials.

Publication types

  • Meta-Analysis

MeSH terms

  • Arthroplasty / adverse effects*
  • Arthroplasty / statistics & numerical data
  • Cervical Vertebrae / surgery*
  • Deglutition Disorders / epidemiology
  • Deglutition Disorders / etiology*
  • Diskectomy / adverse effects*
  • Diskectomy / statistics & numerical data
  • Humans
  • Incidence
  • Spinal Fusion / adverse effects*
  • Spinal Fusion / statistics & numerical data