Ethyl glucuronide for detecting alcohol lapses in patients with an alcohol use disorder

J Addict Med. 2012 Mar;6(1):35-8. doi: 10.1097/ADM.0b013e3182249b93.

Abstract

Urine ethyl glucuronide (EtG) was screened in 75 patients during a hospital-based treatment for an alcohol use disorder. During follow-up, EtG was detected in 35 (14.6%) of the 239 urine samples. Positive screens were found in 22 patients (29%), of whom nine were outpatients (39.1% of all outpatients) and 13 inpatients (25.0% of all inpatients). Of the 22 patients with positive EtG, five (22%) also gave a positive breath alcohol test and 10 (45.5%) reported recent alcohol consumption; 12 (54.5%) gave a negative breath alcohol test and declared no alcohol lapse. Ethyl glucuronide has been found useful in detecting covered lapses.

MeSH terms

  • Adult
  • Alcoholism / rehabilitation*
  • Alcoholism / urine*
  • Biomarkers / urine*
  • Breath Tests
  • Female
  • Glucuronates / urine*
  • Humans
  • Male
  • Mass Screening
  • Middle Aged
  • Predictive Value of Tests
  • Recurrence
  • Residential Treatment
  • Temperance*

Substances

  • Biomarkers
  • Glucuronates
  • ethyl glucuronide